ThreadSpotter performs its analysis on 32 and 64 bit x86 architectures with the following operating systems:
- Linux: Linux 2.6 kernels, 32 and 64-bit operating system and 32 and 64-bit applications
- Microsoft Windows: 32 and 64 bit versions
ThreadSpotter supports most compiled languages such as C, C++, and Fortran and supports most current compilers.